Periodic, multimodal distribution of granule volumes in mast cells.
Periodic, multimodal distribution of granule volumes in mast cells.
复制标题
肥大细胞中颗粒体积的周期性、多峰分布。
DOI：
10.1007/bf00206264
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发表时间：
1983
影响因子：
3.6
通讯作者：
Chi,E
中科院分区：
文献类型：
--
作者：
Hammel,I;Lagunoff,D;Bauza,M;Chi,E
The areas of 2327 mast cell granules in transmission electron micrographs of sections of peritoneal mast cells from adult rats were measured by digitized planimetry. A histogram constructed using equivalent volumes calculated from the measured areas assuming approximation of the granules to spheres showed a periodic multimodal distribution in which the modes fell at volumes that were successively larger integral multiples of the volume at the first mode. Application of a moving-bin technique to the data confirmed the presence of the modes. We propose a mechanism of fusion of unit sized granules to account for the multimodal distribution. The presence of pear- and dumbbell-shaped granules in mast cells is consistent with this mechanism.
