Electrohydrodynamic stretching of DNA in confined environments
Electrohydrodynamic stretching of DNA in confined environments
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DOI：
10.1103/physrevlett.80.2737
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发表时间：
1998-03-23
影响因子：
8.6
通讯作者：
Cox, EC
中科院分区：
文献类型：
--
作者：
Bakajin, OB;Duke, TAJ;Cox, EC
通过观察单个DNA分子在特殊设计的狭缝中与障碍物相互作用时的瞬时伸展和弛豫，研究了限制对聚合物动力学的影响。粘性阻力被发现增加的限制，我们解释的流体动力学筛选方面的平面表面的狭缝的程度。由于DNA是由电泳力驱动的，因此实验数据支持电场作用于拴系的DNA上的观点相当于流体动力学流动。
The effect of confinement on the dynamics of polymers was studied by observing the transient extension and relaxation of single DNA molecules as they interacted with obstacles in a specially designed thin slit. Viscous drag was found to increase with the degree of confinement, which we interpret in terms of hydrodynamic screening by the planar surfaces of the slit. Since the DNA was driven by an electrophoretic force, the experimental data support the notion that an electric field acts on a tethered polyelectrolyte equivalently to a hydrodynamic flow.