High-precision neural stimulation through optoacoustic emitters.
High-precision neural stimulation through optoacoustic emitters.
复制标题
通过光声发射器进行高精度神经刺激。
DOI：
10.1117/1.nph.9.3.032207
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发表时间：
2022-07
期刊：
影响因子：
5.3
通讯作者：
Yang C
中科院分区：
文献类型：
--
作者：
Shi L;Jiang Y;Zheng N;Cheng JX;Yang C
神经调节在破译神经回路和探索神经系统疾病的临床治疗方面发挥着不可估量的作用。光声神经调制是一种新兴的方式，受益于超声的优点，具有高穿透深度以及光子的优点，具有高空间精度。我们总结了神经调制的各种光声平台的最新发展，包括光纤，薄膜和基于纳米传感器的设备，突出每个平台的关键优势。讨论了光声作为一种可行的神经调节工具的可能机制和主要障碍。基础和转化研究的未来方向提出了建议。
Neuromodulation poses an invaluable role in deciphering neural circuits and exploring clinical treatment of neurological diseases. Optoacoustic neuromodulation is an emerging modality benefiting from the merits of ultrasound with high penetration depth as well as the merits of photons with high spatial precision. We summarize recent development in a variety of optoacoustic platforms for neural modulation, including fiber, film, and nanotransducer-based devices, highlighting the key advantages of each platform. The possible mechanisms and main barriers for optoacoustics as a viable neuromodulation tool are discussed. Future directions in fundamental and translational research are proposed.