Foodborne Illness Acquired in the United States-Unspecified Agents

Foodborne Illness Acquired in the United States-Unspecified Agents
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DOI:
10.3201/eid1701.p21101
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发表时间:
2011-01-01
影响因子:
11.8
通讯作者:
Hoekstra, Robert M.
Hoekstra, Robert M.
中科院分区:
医学2区
文献类型:
--
作者:
Scallan, Elaine;Griffin, Patricia M.;Hoekstra, Robert M.

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每年,在美国获得的31种主要已知病原体估计造成940万起食源性疾病。其他疾病发作是由未指明的病原体引起的,包括数据不足以估计病原体特异性疾病的已知病原体、尚未被确认为引起食源性疾病的已知病原体、已知存在于食物中但致病性未经证实的物质以及未知病原体。为了估计这些额外的疾病,我们使用了来自调查、医院记录和死亡证明的数据来估计急性胃肠炎的疾病、住院和死亡,并减去了已知胃肠炎病原体引起的疾病。如果通过家庭食源性传播获得的比例与已知的胃肠炎病原体相似,则估计有3840万人(90%可信区间[Crl] 1980 - 6120万)由未指明病原体引起的国内获得性食源性疾病事件,导致71,878例住院治疗(90% Crl 9,924 - 157,340)和1,686例死亡(90% Crl 369- 3,338)。
Each year, 31 major known pathogens acquired in the United States caused an estimated 9.4 million episodes of foodborne illness. Additional episodes of illness were caused by unspecified agents, including known agents with insufficient data to estimate agent-specific illness, known agents not yet recognized as causing foodborne illness, substances known to be in food but of unproven pathogenicity, and unknown agents. To estimate these additional illnesses, we used data from surveys, hospital records, and death certificates to estimate illnesses, hospitalizations, and deaths from acute gastroenteritis and subtracted illnesses caused by known gastroenteritis pathogens. If the proportions acquired by domestic foodborne transmission were similar to those for known gastroenteritis pathogens, then an estimated 38.4 million (90% credible interval [Crl] 19.8-61.2 million) episodes of domestically acquired foodborne illness were caused by unspecified agents, resulting in 71,878 hospitalizations (90% Crl 9,924-157,340) and 1,686 deaths (90% Crl 369-3,338).