Models for cellular interactions in development without polarity of individual cells II. Problems of synchronization and regulation
Models for cellular interactions in development without polarity of individual cells II. Problems of synchronization and regulation
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发育过程中细胞相互作用的模型，无单个细胞的极性 II。
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发表时间：
1972
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通讯作者：
G. Herman
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作者：
G. Herman
极性的概念在发育生物学中经常被用来解释各种现象。有些作者认为，极性对于某些现象的出现是绝对必要的。在本文中，我们确定了一个单独的细胞的极性与它的能力，以区分在某种意义上它的“左”和“右”的一侧。使用最初由Lindenmayer提出的发育模型，已经证明，如果我们把自己限制在单个细胞没有极性的模型中，这些模型仍然足够普遍，可以实现任何有效的程序。换句话说，它们具有通用的计算能力。然而，已经证明，在单元的线性阵列中，各个单元必须具有极性，以便表现出某些种类的调节行为，即在显著的外部干扰（例如，阵列分裂成两个不连接的阵列）之后恢复阵列的某些全局特性。我们证明了一个…
The notion of polarity is often used in developmental biology for the explanation of various phenomena. Some authors have considered that polarity is absolutely essential for certain kinds of phenomena to appear. In this paper, we identify polarity of an individual cell with its ability to distinguish in somo sense between its ‘ left’ and its ‘ right ’ side. It has been shown, using a developmental model originally due to Lindenmayer, that oven if we restrict ourselves to models in which individual cells have no polarity, the models remain general enough to realize any effective procedure. In other words, they have a universal computing ability. However, it has been conjectured that, in a linear array of cells, the individual cells must have polarity in order to exhibit certain kinds of regulatory behaviour, i.e. the regaining of certain global properties of the array after a significant external disturbance (for example, the breaking of the array into two disconnected arrays). We demonstrate that one suc...