A monoclonal antibody that recognizes B cells and B cell precursors in mice.
A monoclonal antibody that recognizes B cells and B cell precursors in mice.
复制标题
DOI：
10.1084/jem.153.2.269
复制
发表时间：
1981-02-01
影响因子：
15.3
通讯作者：
Weissman, I L
中科院分区：
文献类型：
--
作者：
Coffman, R L;Weissman, I L
The monoclonal antibody, RA3-2C2, appears to be specific for cells within the B cell lineage. This antibody does not recognize thymocytes, peripheral T cells, or nonlymphoid hematopoietic cells in the spleen or bone marrow. Nor does it recognize the pluripotent hematopoietic stem cells, the spleen colony-forming unit, All sIg+ B cells and most plasma cells are RA3-2C2+. In addition, approximately 20% of nucleated bone marrow cells are RA3-2C2+ but sIg-. This population contains B cell precursors that can give rise to sIg+ cells within 2 d in vitro.
