Pilosebaceous abnormalities in Apert's syndrome.
Pilosebaceous abnormalities in Apert's syndrome.
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阿珀特综合征中的毛囊皮脂腺异常。
DOI：
10.1001/archderm.1970.04000100029007
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发表时间：
1970
影响因子：
--
通讯作者：
S. Pruzansky
中科院分区：
文献类型：
--
作者：
L. Solomon;D. Fretzin;S. Pruzansky
9例Apert综合征（尖头并指）患者的临床结果显示，7例青春期后患者在面部、胸部、背部和前臂（以一种不寻常的方式）广泛存在中度至重度寻常痤疮。由于前臂痤疮是罕见的，在一组Apert综合征患者中，这种发现的频率没有额外的男性化证据，表明他们可能有终末器官雄激素分布异常。
The clinical findings in nine patients with Apert's syndrome (acrocephalosyndactyly) revealed seven postpuberal patients to have widespread moderate-to-severe acne vulgaris on the face, chest, back, and in an unusual manner, the forearms. Since forearm acne is rare, the frequency of this finding without additional evidence of virilization in a group of patients with Apert's syndrome suggested they may have an abnormality of end-organ androgen disposition.