Assessment of quantitative methods for 2-dimensional echocardiography.
Assessment of quantitative methods for 2-dimensional echocardiography.
复制标题
二维超声心动图定量方法的评估。
DOI：
10.1016/0002-9149(83)90146-7
复制
发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Corday,E
中科院分区：
文献类型：
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作者：
Wyatt,HL;Haendchen,RV;Meerbaum,S;Corday,E
几种二维超声心动图(2-DE)方法在体外测试了线性和横断面测量的准确性，并在体内测试了左心室(LV)容量重建的准确性。在2-DE仪器设置为低增益和高增益，以及精确的体外校准的情况下，我们研究了心肌切片厚度(3.0到10.0 mm)。2-DE心肌厚度测量采用导联、拖带、导联三种方法。2-DE与直接测量的回归分析为所有3种方法产生了良好的相关性(r>；0.985)，观察者间的变异性为3%。只有领先方法的测量精度令人满意(在低增益和高增益时误差分别为3%和6%)；其他方法大大高估或低估了厚度。将厚度为1 mm的心肌薄片贴在圆柱体上，并用福尔马林固定，以产生精确的空洞面积(1.8~7.0cm2)。2-DE与实际空洞面积的回归分析显示，内缘法和前缘法的相关性很高(r>；0.970)，观察者间的变异性很低(<；4%)，但前缘法最准确(误差为1.3%~2.5%)。用2-DE和电影血管造影术比较了7只麻醉犬的在体左心室体积。相关性良好(r=0.92)，但内缘法低估了血管造影量，而前沿法减少了低估的幅度。因此，2-DE的前沿方法不仅对心肌的线性和横断面测量是最准确的，而且对于活体左心室体积的应用也是最准确的。
Several 2-dimensional echocardiographic (2-DE) methods were tested in vitro for accuracy of linear and cross-sectional measurements and in vivo for left ventricular (LV) volume reconstruction. With 2-DE instrument settings at low and high gains and with precise in vitro calibrations, we studied myocardial slice thickness (3.0 to 10.0 mm). The 2-DE myocardial thickness was measured by leadingtrailing, trailing-leading, and leading-leading methods. Regression analysis of 2-DE versus direct measurements yielded excellent correlations for all 3 methods (r > 0.985), with interobserver variability < 3%. Accuracy of measurement was satisfactory only for the leading-leading method (3 and 6% error at low and high gains, respectively); other methods substantially over- or underestimated thickness. Thin myocardial slices (< 1 mm thick) were applied to cylinders and fixed in formalin to produce precise cavity areas (1.8 to 7.0 cm2). Regression analysis of 2-DE versus actual cavity area gave high correlations (r > 0.970), and low interobserver variability (< 4%) for the inner edge and leading edge methods, but the leading edge method was the most accurate (1.3 to 2.5% error). In vivo LV volumes in 7 anesthetized dogs were compared with 2-DE and cineangiography. Good correlations (r = 0.92) were obtained, but the inner edge method underestimated angiographic volume, whereas the leading edge method reduced the magnitude of underestimation. Thus, the leading edge method for 2-DE is most accurate not only for linear and cross-sectional measurements of the myocardium, but also for application to in vivo LV volumes.