SEROLOGICAL SURVEY FOR ARTHROPOD-BORNE VIRUS INFECTIONS IN THE PHILIPPINES
SEROLOGICAL SURVEY FOR ARTHROPOD-BORNE VIRUS INFECTIONS IN THE PHILIPPINES
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DOI：
10.4269/ajtmh.1958.7.323
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发表时间：
1958-01-01
影响因子：
3.3
通讯作者：
SATHER, GE
中科院分区：
文献类型：
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作者：
HAMMON, WM;SCHRACK, WD;SATHER, GE
从马尼拉100英里范围内的菲律宾吕宋岛的菲律宾土著人、黑人、马和水牛中收集了数百份血清。从三个不同的生态区选择种群。这些血清主要通过中和试验检测15种节肢动物传播的人畜共患病病毒的抗体。所涉及的病毒，因为它们有许多抗原性重叠，不能全部仅根据血清学反应来鉴定。然而，极有可能存在日本B脑炎病毒、登革热病毒和东方马脑炎病毒，以及至少两种来自B组的病毒（其中一种可能是Ntaya病毒）和至少另一种来自A组的病毒，如果不是塞姆利基森林病毒，则与该病毒密切相关。由于这一初步调查，组织了一次考察，试图分离并实际查明在场的制剂。对后者材料的测试仍在进行中。
Several hundred sera were collected from native Filipinos, Negritos, horses and carabao on Luzon, Philippine Islands in an area within 100 miles of Manila. Populations were selected from three different ecological areas. These sera were tested principally by neutralization tests for antibodies to 15 members of the arthropod-borne zoonoses viruses. The viruses involved, because of their many antigenic overlappings, could not all be identified on the basis ef serological response alone. It appears highly probable, however, that Japanese B encephalitis, dengue and Eastern equine encephalitis virus are present, plus at least two others from group B (one of these possibly Ntaya) and at least one other from group A, closely related to Semliki Forest virus if not that virus. As a result of this preliminary survey an expedition was organized to attempt to isolate and thus actually identify the agents present. Testing of these latter materials is still under way.