Measurement of vertebral kinematics using noninvasive image matching method - Validation and application
Measurement of vertebral kinematics using noninvasive image matching method - Validation and application
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DOI：
10.1097/brs.0b013e3181715295
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发表时间：
2008-05-15
期刊：
影响因子：
3
通讯作者：
Wood, Kirkham
中科院分区：
文献类型：
--
作者：
Wang, Shaobai;Passias, Peter;Wood, Kirkham
研究设计。体外和体内实验研究。验证双透视图像匹配技术在体内脊柱运动学测量。背景资料摘要。准确了解脊柱结构功能对于理解影响脊柱病理的生物力学因素至关重要。许多研究研究了体外和体内的椎体运动。然而，由于现有技术的限制和脊柱复杂的解剖结构，在生物医学工程中，确定生理负荷条件下椎骨的体内运动仍然是一个挑战。在体外验证中，通过MTS机器以已知的速度将羊脊柱移动到已知的距离。采用双透视系统捕捉脊柱运动并重现运动距离和速度。在体内验证中，活体受试者在负重下以不同的姿势移动脊柱。利用荧光镜再现体内脊柱位置5次。用5个测量值的平移和方向标准差来评价技术的可重复性。基于磁共振图像的椎体模型图像匹配技术可以确定羊脊柱的平移位置，平均精度小于0.40 mm。该方法对人体脊柱6DOF运动的再现精度为0.2 mm/ s，平移精度小于0.3 mm，方向精度小于0.7°。图像匹配技术是准确和可重复的无创测量脊柱椎体运动。该技术可作为脊柱病理手术治疗前后确定椎体位置和方向的有用工具，以评估和提高各种手术方法在恢复正常脊柱功能方面的疗效。
Study Design. In vitro and in vivo laboratory study.Objective. To validate a dual fluoroscopic image matching technique for measurement of in vivo spine kinematics.Summary of Background Data. Accurate knowledge of the spinal structural functions is critical to understand the biomechanical factors that affect spinal pathology. Many studies have investigated vertebral motion both in vitro and in vivo. However, determination of in vivo motion of the vertebrae under physiologic loading conditions remains a challenge in biomedical engineering because of the limitations of current technology and the complicated anatomy of the spine.Methods. In in vitro validation, an ovine spine was moved to a known distance in a known speed by an MTS machine. The dual fluoroscopic system was used to capture the spine motion and reproduce the moving distance and speed. In in vivo validation, a living subject moved the spine in various positions under weightbearing. The fluoroscopes were used to reproduce the in vivo spine positions 5 times. The standard deviations in translation and orientation of the 5 measurements were used to evaluate the repeatability of technique.Results. The translation positions of the ovine spine could be determined with a mean accuracy less than 0.40 mm for the image matching technique using magnetic resonance image- based vertebral models. The spine speed could be reproduced within an accuracy of 0.2 mm/ s. The repeatability of the method in reproducing in vivo human spine 6DOF kinematics was less than 0.3 mm in translation and less than 0.7 degrees in orientation.Conclusion. The image matching technique was accurate and repeatable for noninvasive measurement of spine vertebral motion. The technique could be a useful tool for determination of vertebral positions and orientations before and after surgical treatment of spinal pathology to evaluate and improve the efficacy of the various surgical methods in restoring normal spine function.