Neuritic growth and neuroma formation by an isolated molluscan ganglion.
Neuritic growth and neuroma formation by an isolated molluscan ganglion.
复制标题
孤立的软体动物神经节的神经炎生长和神经瘤形成。
DOI：
10.1002/neu.480130110
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Bulloch,AG
中科院分区：
文献类型：
--
作者：
Stamler,JF;Kater,SB;Murphy,AD;Bulloch,AG
蜗牛 Helisoma trivolvis 的分离的成对颊神经节在体内（即在宿主蜗牛中）培养长达 377 天。这种神经节通常被白色的纤维组织团包裹，在四个星期内达到最大尺寸。扫描电子显微镜显示新形成的组织由细纤维组成，这些纤维也遍布神经纤维。向单个神经元注射荧光黄 CH 会填充组织块内的许多新神经突。结论是这些肿块主要是神经元起源的，因此它们被指定为神经瘤。神经瘤的最大尺寸可能受到限制神经元体积的内在机制的限制。
The isolated, paired buccal ganglia of the snailHelisoma trivolviswere culturedin vivo(i.e., in host snails) for periods up to 377 days. Such ganglia typically become enveloped in a white mass of fibrous tissue which reaches a maximum plateau of size within four weeks. The scanning electron microscope revealed the newly formed tissue to be composed of fine fibers which also pervaded the neuropil. Injection of individual neurons with Lucifer Yellow CH filled many new neurites within the tissue mass. It is concluded that these masses are largely of neuronal origin and they are therefore designated as neuromas. The maximum size of neuromas may be limited by intrinsic mechanisms which limit neuronal volume.