Analyte-induced aggregation of a water-soluble conjugated polymer for fluorescent assay of oxalic acid
Analyte-induced aggregation of a water-soluble conjugated polymer for fluorescent assay of oxalic acid
复制标题
用于草酸荧光测定的水溶性共轭聚合物的分析物诱导聚集
DOI：
10.1002/marc.200700301
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发表时间：
2007-09-18
影响因子：
4.6
通讯作者：
Wang, Shu
中科院分区：
文献类型：
--
作者：
Sun, Huan;Feng, Fude;Wang, Shu
已开发了一种测定方法，使用阳离子聚噻吩衍生物（PFT）从其他结构相似的二羧酸中检测草酸。加入草酸后，PFT可通过草酸的双官能二元酸交联，形成紧密的共聚体π中心点中心点堆积聚集体，导致PFT的荧光自猝灭。在添加具有较长系链的其他二羧酸时，松散的互聚物π-堆积聚集体形成，并且PFT荧光较少淬灭。在沉淀之前在溶液中对聚集体进行荧光分析。由于草酸的短系链，来自PFT/草酸组装体的独特荧光响应可用于检测草酸。
An assay method has been developed to detect oxalic acid from other structurally similar dicarboxylic acids using a cationic polythiophene derivative (PFT). Upon adding oxalic acid, the PFT can be cross-linked through the bifunctional diacids of oxalic acid to form tense interpolymer pi center dot center dot stacking aggregation, which results in the fluorescence self-quenching of the PFT. Upon adding other dicarboxylic acids with a longer tether, loose interpolymer pi-stacking aggregation forms and the PFT fluorescence is less quenched. The fluorescence analysis was carried out in solution for the aggregates prior to precipitation. As a result of the short tether of oxalic acid, the unique fluorescent response from the PFT/oxalic acid assembly can be used to detect oxalic acid.