ADENOMATOUS AND CARCINOMATOUS CHANGES WITHIN HYPERPLASTIC COLONIC EPITHELIUM
ADENOMATOUS AND CARCINOMATOUS CHANGES WITHIN HYPERPLASTIC COLONIC EPITHELIUM
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DOI：
10.1007/bf02586805
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发表时间：
1979-01-01
影响因子：
3.9
通讯作者：
MARKS, G
中科院分区：
文献类型：
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作者：
COOPER, HS;PATCHEFSKY, AS;MARKS, G
增生性结肠息肉是良性的非肿瘤性增生。与管状和绒毛状腺瘤不同，它们不会使患者易患结肠癌。从理论上讲，这些增生性息肉，像正常的结肠上皮一样，应该能够经历腺瘤性转化，并可能发展成癌症。一个不寻常的情况下，一个病人有许多增生性息肉，其中腺瘤的变化发生和癌症的发展进行了讨论，这些变化的意义，因为它们涉及到息肉癌序列也进行了讨论。
Hyperplastic colonic polyps are benign, non-neoplastic proliferations. Unlike tubular and villous adenomas, they do not predispose the patient to colonic cancer. Theoretically, these hyperplastic polyps, like normal colonic epithelium, should be able to undergo adenomatous transformation and possibly develop into cancer. An unusual case of a patient with numerous hyperplastic polyps, in which adenomatous changes occurred and cancer developed is discussed; the significance of these changes as they relate to the polyp-cancer sequence are also discussed.