Integration of Radiation Therapy and Systemic Therapy for Breast Cancer

Integration of Radiation Therapy and Systemic Therapy for Breast Cancer
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乳腺癌放射治疗与全身治疗的整合

DOI:
10.1007/3-540-35662-2_17
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发表时间:
2006
影响因子:
7.4
通讯作者:
T. Buchholz
T. Buchholz
中科院分区:
医学1区
文献类型:
--
作者:
Seungtaek L. Choi;H. Thames;T. Buchholz

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在过去的20年里,乳腺癌的治疗取得了重大进展。辅助放射治疗,化疗和激素治疗都被证明可以改善无事件和总体生存率,现在是乳腺癌管理标准治疗的一部分。尽管在确定这些治疗的最佳组合和排序方面已经取得了重大进展,但仍需要进一步的研究来更好地将这些治疗相互结合。此外,新的治疗方法,如芳香化酶抑制剂和曲妥珠单抗,也需要与传统治疗相结合,以最大限度地提高其有效性并减少其毒性;因此,必须再次强调外科医生、放射肿瘤学家、内科肿瘤学家、病理学家和诊断放射学家参与的乳腺癌多学科管理的重要性。
The last 20 years have yielded significant advances in the treatment of breast cancer. Adjuvant radiation therapy, chemotherapy, and hormonal therapy have all been shown to improve event-free and overall survival and are now part of the standard treatment in the management of breast cancer. Although there has been significant progress in determining the optimal combination and sequencing of these treatments, additional studies are still required to better integrate these therapies with each other. Furthermore, newer treatments, such as aromatase inhibitors and trastuzumab, also need to be integrated with conventional therapies to maximize their effectiveness and minimize their toxicity; therefore, the importance of the multidisciplinary management of breast cancer, with participation of the surgeons, radiation oncologists, medical oncologists, pathologists, and diagnostic radiologists, must once again be emphasized.
DOI: 10.1093/oxfordjournals.jncimonographs.a003469
发表时间: 2001-12
期刊: Journal of the National Cancer Institute. Monographs
影响因子: --
作者:
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