Sudden re-opening of collapsed transverse sinuses and longstanding clinical remission after a single lumbar puncture in a case of idiopathic intracranial hypertension. Pathogenetic implications
Sudden re-opening of collapsed transverse sinuses and longstanding clinical remission after a single lumbar puncture in a case of idiopathic intracranial hypertension. Pathogenetic implications
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DOI：
10.1007/s10072-004-0368-3
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发表时间：
2005-02-01
影响因子：
3.3
通讯作者：
Bonavita, V
中科院分区：
文献类型：
--
作者：
De Simone, R;Marano, E;Bonavita, V
大多数特发性颅内高压（IIH）患者的窦静脉阻塞的病因作用是有争议的。我们报告的情况下，一名年轻女子诊断为IIH与乳头水肿和横窦狭窄，其中降低颅内压的单一20毫升脑脊液（CSF）导致了强烈的尺寸增加横窦。变化后，临床缓解和视神经口径正常化，维持2个月的随访后。我们的研究结果表明，虽然继发于脑脊液高血压，静脉窦压迫可能有一个重要的作用，在高血压状态的维持。高血压性脑脊液压迫静脉窦的发病机制进行了讨论。
The aetiopathogenetic role of sinus venous obstructions carried by most idiopathic intracranial hypertension (IIH) patients is controversial. We report the case of a young woman diagnosed with IIH with papilloedema and narrowing of transverse sinuses, in which lowering of intracranial pressure by a single 20 ml cerebrospinal fluid (CSF) resulted in a strong dimensional increase of the transverse sinuses. Changes were followed by clinical remission and normalisation of optical nerve calibre, maintained after a 2-month follow-up. Our findings indicate that, although secondary to CSF hypertension, venous sinuses compression may have an important role in hypertensive status maintenance. Pathogenetic implications of venous sinus compression by hypertensive CSF in IIH are discussed.