HAS NEGATIVE STAINING STILL A PLACE IN BIOMACROMOLECULAR ELECTRON-MICROSCOPY
HAS NEGATIVE STAINING STILL A PLACE IN BIOMACROMOLECULAR ELECTRON-MICROSCOPY
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DOI：
10.1016/0304-3991(92)90008-8
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发表时间：
1992-10-01
期刊：
影响因子：
2.2
通讯作者：
AEBI, U
中科院分区：
文献类型：
--
作者：
BREMER, A;HENN, C;AEBI, U
Transmission electron microscopy of proteins has provided molecular- and in a few cases near-atomic-resolution structural information. In this review, we critically evaluate the potential and the limitations in obtaining molecular resolution, particularly with negatively stained specimens, and put these into perspective with cryomicroscopy of unstained frozen-hydrated and sugar-embedded preparations.
