Prelude to and resolution of an error: EEG phase synchrony reveals cognitive control dynamics during action monitoring.
Prelude to and resolution of an error: EEG phase synchrony reveals cognitive control dynamics during action monitoring.
复制标题
DOI：
10.1523/jneurosci.4137-08.2009
复制
发表时间：
2009-01-07
期刊：
影响因子：
--
通讯作者：
Allen JJ
中科院分区：
文献类型：
--
作者：
Cavanagh JF;Cohen MX;Allen JJ
在内侧前额叶皮层（mPFC）中与错误相关的活动被认为与外侧前额叶皮层（lPFC）一起工作，作为行动监测网络的一部分，错误表明需要加强认知控制。mPFC-lPFC相互作用发生的神经机制尚不清楚。我们假设theta范围内的瞬态同步振荡反映了这些结构相互作用的机制。为了验证这一假设，我们从Flanker任务期间记录的电流源密度转换脑电图数据中提取了振荡相位和功率。在实验中，mPFC的θ波功率在错误发生前降低，在错误发生后立即增加，这与动作监测系统的预测一致。这些功率动态似乎发生在与响应相关的振荡θ相位相干背景上。误差试验期间，FCz （mPFC）和F5/6 （lPFC）位点之间的Theta相位同步明显增加。mPFC- lpfc振荡同步程度预测误差试验时mPFC功率的大小，这两种动态预测误差后反应时间减慢的大小。θ波段的振荡动力学可能在一定程度上解释了参与动作监测和认知控制的神经网络之间的交流机制。
Error-related activity in the medial prefrontal cortex (mPFC) is thought to work in conjunction with lateral prefrontal cortex (lPFC) as a part of an action monitoring network, where errors signal the need for increased cognitive control. The neural mechanism by which this mPFC-lPFC interaction occurs remains unknown. We hypothesized that transient synchronous oscillations in the theta range reflect a mechanism by which these structures interact. To test this hypothesis, we extracted oscillatory phase and power from current–source-density-transformed electroencephalographic data recorded during a Flanker task. Theta power in the mPFC was diminished on the trial preceding an error and increased immediately following an error, consistent with predictions of an action monitoring system. These power dynamics appeared to take place over a response-related background of oscillatory theta phase coherence. Theta phase synchronization between FCz (mPFC) and F5/6 (lPFC) sites was robustly increased during error trials. The degree of mPFC-lPFC oscillatory synchronization predicted the degree of mPFC power on error trials, and both of these dynamics predicted the degree of post-error reaction time slowing. Oscillatory dynamics in the theta band may in part underlie a mechanism of communication between networks involved in action monitoring and cognitive control.