STUDIES ON OPISTHORCHIS-VIVERRINI IN THAILAND
STUDIES ON OPISTHORCHIS-VIVERRINI IN THAILAND
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DOI：
10.1093/oxfordjournals.aje.a119772
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发表时间：
1955-01-01
影响因子：
--
通讯作者：
SADUN, EH
中科院分区：
文献类型：
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作者：
SADUN, EH
在泰国各省对人类和猫的粪便检查中发现的吸虫卵在形态上非常相似，并且与对猫尾后睾吸虫的描述相似。卵的平均大小为27 × 15 [mu]。人源和猫源的吸虫成虫也非常相似，符合O。维韦里尼。它们的平均尺寸分别为7 × 1.5 mm和4.6 × 2 mm。根据26，000多份粪便检查，后睾吸虫感染在我国调查的所有省份都是人类的地方病。n. - e.泰国，但不是在任何部分的中央和s。地区最重要的流行区在湄公河流域。在感染严重的地区，约50%的受检者携带这种感染。暹罗人和中国人的感染率有显著差异，在一个城市分别为50.4和2.9。在性别之间或城市和农村人口之间没有发现显著差异。通过虫卵计数测量的感染强度与发病率结果密切相关。随着年龄的增长，感染的发生率和强度逐渐增加。据估计，泰国有150万至200万人感染肝吸虫，其中大多数生活在东北部。在泰国，生鱼经常被食用，特别是生活在越南的老挝人。e.而在N。地区当猫被喂食一些在市场上出售的供人类食用的常见鱼类菜肴时，肝吸虫感染产生了。居住在同一城镇的暹罗人和中国人之间以及不同年龄段人群之间的发病率和强度差异主要与他们的饮食习惯有关。猫和狗被发现自然感染后睾吸虫，不仅在肝吸虫在人类中高度流行的地区，而且在泰国中部以及从未遇到过土著人类感染的地区。在一个高度流行的村庄对143人进行的密切观察表明，随着感染年龄的增长和吸虫的逐渐获得，人后睾吸虫病的症状逐渐加重。未发现与感染相关的显著嗜酸性粒细胞增多。肝硬化和胆管癌在东北地区是常见病。在4例感染后睾吸虫的成年男性中，尸检时诊断为胆管癌。其中一个有5996只成虫。
Trematode eggs found in fecal examinations of humans and cats in various provinces in Thailand were morphologically quite alike and similar to those described for Opisthorchis viverrini. The average size of eggs was 27 by 15 [mu]. The adult flukes from human and cat sources were also quite alike and fitted the description of O. viverrini. They measured on the average 7 by 1.5 mm and 4.6 by 2 mm, respectively. On the basis of over 26,000 stool examinations, Opisthorchis infection is endemic in humans in all the provinces surveyed in the n. and n.-e. Thailand but not in any part of the central and s. regions. The most important endemic areas are in the Mekong Valley. In the areas of heavy infection about 50% of persons examined harbored this infection. A striking difference in incidence of infection was observed between the Siamese and Chinese, in one city being 50.4 and 2.9, respectively. No significant differences was found between sexes or between urban and rural populations. Intensity of infection as measured by egg counts closely paralleled the incidence findings. A gradual increase in incidence and intensity of infection with age was observed. It is estimated that between 1.5 and 2 million persons have liver fluke infections in Thailand, most of them living in the northeast. Raw fish is frequently eaten in Thailand, particularly by the Laos living in the n.-e. and in the n. regions. When cats were fed some of the common fish dishes sold at a market for human consumption, infection with the liver fluke was produced. The difference in incidence and intensity between the Siamese and Chinese living in the same town, and between people at different age levels was related primarily to their dietary habits. Cats and dogs were found naturally infected with Opisthorchis not only in those regions where liver fluke is highly endemic in man but in central Thailand as well where indigenous human infections were never encountered. Close observation of 143 persons in a highly endemic village indicated that symptoms in human opisthorchiasis progressively increase in severity as the infection becomes older and as the flukes are gradually acquired. No marked eosinophilia was found associated with the infection. Liver cirrhosis and carcinoma of the bile ducts were often observed among the people living in the northeast. In 4 adult males infected with Opisthorchis a diagnosis of carcinoma of the bile ducts was established at autopsy. One of them harbored 5996 adult flukes.