Elevated plasma apolipoprotein AV in acute coronary syndrome is positively correlated with triglyceride and C-reactive protein
Elevated plasma apolipoprotein AV in acute coronary syndrome is positively correlated with triglyceride and C-reactive protein
复制标题
急性冠脉综合征血浆载脂蛋白AV升高与甘油三酯和C反应蛋白呈正相关
DOI：
10.3760/cma.j.issn.0366-6999.2009.12.010
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发表时间：
2009-06-20
影响因子：
6.1
通讯作者：
Hu Min
中科院分区：
文献类型：
--
作者：
Huang Xian-sheng;Zhao Shui-ping;Hu Min
背景：甘油三酯（TG）升高发生在急性冠脉综合征（ACS）患者中，载脂蛋白AV （apoAV）已被证明可以降低TG水平。在本研究中，我们研究了ACS患者血浆apoAV水平及其与TG和c反应蛋白（CRP）的关系。方法共招募459例受试者，分为对照组（116例）、稳定期心绞痛组（115例）、不稳定期心绞痛组（116例）和急性心肌梗死组（112例）。采用夹心ELISA法检测血浆apoAV水平。结果与对照组((100.27+/-22.44)ng/ml相比，SA患者血浆apoAV降低（(76.54+/-16.91)ng/ml），而不稳定型心绞痛患者血浆apoAV升高((330.89+/-66.48)ng/ml， P
Background Increased triglyceride (TG) occurs in patients with acute coronary syndrome (ACS), and apolipoprotein AV (apoAV) has been shown to lower TG levels. In the present study, we investigated plasma apoAV level and its relationship with TG and C-reactive protein (CRP) in ACS patients.Methods A total of 459 subjects were recruited and categorized into control group (n=116), stable angina (SA) group (n=115), unstable angina group (n=116) and acute myocardial infarction group (n=112). Plasma apoAV level was measured by a sandwich ELISA assay.Results Compared with controls ((100.27+/-22.44) ng/ml), plasma apoAV was decreased in SA patients ((76.54+/-16.91) ng/ml) but increased in patients with unstable angina ((330.89+/-66.48) ng/ml, P