The extended auricle1 (eta1) gene is essential for the genetic network controlling postinitiation maize leaf development.
The extended auricle1 (eta1) gene is essential for the genetic network controlling postinitiation maize leaf development.
复制标题
扩展的 auricle1 (eta1) 基因对于控制启动后玉米叶片发育的遗传网络至关重要。
DOI：
10.1093/genetics/165.3.1507
复制
发表时间：
2003
期刊：
影响因子：
3.3
通讯作者：
Freeling,Michael
中科院分区：
文献类型：
--
作者：
Osmont,KarenS;Jesaitis,LynneA;Freeling,Michael
玉米叶片由具有清晰形态边界的不同区域组成。叶舌和叶耳标志着远侧叶片和近侧鞘之间的边界，并且由于影响其形成而不严重影响生存能力的突变体阵列而适合于遗传研究。在这里，我们描述了新的玉米基因extended auricle 1（eta 1），这是必要的叶片/鞘边界的正确形成。Homozygouseta 1个体的耳廓组织呈波浪状过度生长，叶鞘边界呈弥漫性。feta 1与knox和ligulelesspathway基因的双突变组合导致协同作用，在某些情况下，剂量依赖性相互作用。虽然eta 1突变体个体的表型与显性knox过表达表型相似，但eta 1突变体叶子不会异位表达knox基因。此外，eta 1与lg 1和lg 2协同作用，但不直接影响叶原基中任一基因的转录。我们提出的证据基于遗传和分子分析，teta 1提供了knox和舌途径之间的下游联系。
The maize leaf is composed of distinct regions with clear morphological boundaries. The ligule and auricle mark the boundary between distal blade and proximal sheath and are amenable to genetic study due to the array of mutants that affect their formation without severely affecting viability. Herein, we describe the novel maize geneextended auricle1(eta1), which is essential for proper formation of the blade/sheath boundary. Homozygouseta1individuals have a wavy overgrowth of auricle tissue and the blade/sheath boundary is diffuse. Double-mutant combinations ofeta1with genes in theknoxandligulelesspathways result in synergistic and, in some cases, dosage-dependent interactions. While the phenotype ofeta1mutant individuals resembles that of dominantknoxoverexpression phenotypes,eta1mutant leaves do not ectopically expressknoxgenes. In addition,eta1interacts synergistically withlg1andlg2, but does not directly affect the transcription of either gene in leaf primordia. We present evidence based on genetic and molecular analyses thateta1provides a downstream link between theknoxandligulelesspathways.