Functional development of grafted vasopressin neurons.
Functional development of grafted vasopressin neurons.
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移植的加压素神经元的功能发育。
DOI：
10.1126/science.7434031
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Sladek,CD
中科院分区：
文献类型：
--
作者：
Gash,D;SladekJr,JR;Sladek,CD
将正常大鼠胎儿的抗利尿激素神经元移植到成年伯氏大鼠第三脑室，可减轻宿主的多饮和多尿。测定先天性尿囊症宿主移植神经元的抗利尿活性，为分析哺乳动物移植中枢神经系统神经元的发育、可塑性和功能提供了方便的模型。
Vasopressin neurons, transplanted from normal rat fetuses into the third ventricle of adult Brattleboro rats, alleviate the polydipsia and polyuria of the hosts. Determination of the antidiuretic activity of grafted neurons in hosts with congenital diabetes insipidus provides a convenient model for analyzing the development, plasticity, and function of transplanted central nervous system neurons in mammals.