Expanding capsules
Expanding capsules
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DOI：
10.1080/10610270802549691
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发表时间：
2009-01-01
影响因子：
3.3
通讯作者：
Rebek, Julius, Jr.
中科院分区：
文献类型：
--
作者：
Ajami, Dariush;Rebek, Julius, Jr.
通过氢键结合在一起的自组装胶囊包含间隔模块，该间隔模块延长胶囊的长度并增加其容量。该模块是甘脲衍生物，提供适当的分子曲率和互补的氢键表面。四个甘脲模块以手性排列插入胶囊中，并允许封装较长的客人。具体地说，正十四烷是原始胶囊容纳的最长的客体，但正构烷烃C15-C19适合扩展胶囊。氢键结合的二聚体胶囊可以用4、8或12个甘脲间隔物膨胀，使腔的体积增加至5303，长度增加至21。扩展的组件是手性的，并封装了各种较长的正构烷烃。大量的分子胶囊可以从一个小的积木集合中产生。一个氢键二聚体胶囊可以用4个、8个和12个甘脲间隔物扩张，使空腔的体积增加到530埃3，长度增加到21埃。[图片省略]。
A self-assembled capsule held together by hydrogen bonding incorporates spacer modules that extend the capsule's length and increase its capacity. The modules are glycoluril derivatives that provide appropriate molecular curvature and complementary hydrogen bonding surfaces. Four glycoluril modules insert into the capsule in a chiral arrangement and allow encapsulation of longer guests. Specifically, n-tetradecane is the longest guest accommodated by the original capsule, but normal alkanes C15-C19 fit into the extended capsule. The hydrogen bonded, dimeric capsule can be expanded with 4, 8 or 12 glycoluril spacers that increase the cavity's volume by up to 5303 and length by 21. The extended assemblies are chiral and encapsulate a variety of longer normal alkanes. A large variety of molecular capsules can be created from just a small collection of building blocks. A hydrogen-bonded, dimeric capsule can be expanded with 4, 8 and 12 glycoluril spacers that increase the cavity's volume by up to 530A3 and length by21A.[image omitted].