Recent Changes in the Patterns of Breast Cancer as a Proportion of All Deaths According to Race and Ethnicity.
Recent Changes in the Patterns of Breast Cancer as a Proportion of All Deaths According to Race and Ethnicity.
复制标题
DOI：
10.1097/ede.0000000000001394
复制
发表时间：
2021-11-01
期刊：
影响因子：
--
通讯作者：
Gangnon RE
中科院分区：
文献类型：
--
作者：
Trentham-Dietz A;Chapman CH;Bird J;Gangnon RE
最近的报告表明，乳腺癌发病率的种族差异已经减少。我们研究了这些发现是否适用于乳腺癌死亡率，同时考虑了年龄、周期和队列对乳腺癌死亡率的绝对和相对指标的影响。使用公开的数据集(CDC Wonder，人类死亡率数据库)，我们建立了一个年龄时期队列模型，研究1968-2019年所有女性和五个种族/民族群体的乳腺癌死亡率和乳腺癌死亡占所有死亡人数的比例，这些种族/民族群体有足够的数字可供估计：西班牙裔(所有种族)、美国印第安人/阿拉斯加原住民和亚洲/太平洋岛民(不分种族)、非西班牙裔黑人和非拉美裔白人。1968年后，经年龄调整的乳腺癌死亡率最初上升，但自1988年以来，所有种族/民族的乳腺癌死亡率均有所下降。自1990年左右以来，非西班牙裔白人女性死于乳腺癌的年龄调整后百分比也一直在下降，而其他种族/民族的比例则有所上升或保持稳定。2019年，亚洲/太平洋岛民女性死于乳腺癌的年龄调整百分比最高(5.6%)，其次是非西班牙裔黑人(4.5%)、西班牙裔(4.4%)、非西班牙裔白人(4.1%)和美国印第安人/阿拉斯加土著妇女(2.6%)。现在，非西班牙裔黑人妇女的乳腺癌死亡率差距在相对和绝对范围内都更大，使用亚洲/太平洋岛民和西班牙裔妇女的相对范围，与50年来第一次非西班牙裔白人妇女相比。
Recent reports suggest that racial differences in breast cancer incidence rates have decreased. We examined whether these findings apply to breast cancer mortality while considering age, period, and cohort influences on both absolute and relative measures of breast cancer mortality. Using publicly available datasets (CDC Wonder, Human Mortality Database), we developed an age-period-cohort model of breast cancer mortality and breast cancer deaths as a proportion of all deaths during 1968–2019 among all women and by five race/ethnicity groups with sufficient numbers for estimation: Hispanic (all races), American Indian/Alaska Native and Asian/Pacific Islanders (regardless of ethnicity), non-Hispanic Black, and non-Hispanic White. Initially increasing after 1968, age-adjusted breast cancer mortality rates have decreased among all racial/ethnic groups since 1988. The age-adjusted percent of all deaths due to breast cancer also has been declining for non-Hispanic White women since about 1990 while increasing or holding steady for other race/ethnic groups. In 2019, the age-adjusted percent of deaths due to breast cancer for women was highest for Asian/Pacific Islanders (5.6%) followed by non-Hispanic Black (4.5%), Hispanic (4.4%), non-Hispanic White (4.1%), and American Indian/Alaska Native women (2.6%). Breast cancer mortality disparities are now greater on both relative and absolute scales for non-Hispanic Black women, and using the relative scale for Asian/Pacific Islander and Hispanic women, compared with non-Hispanic White women for the first time in 50 years.