Bioaccumulation of legacy organic contaminants in pregnant Indo-Pacific humpback dolphins (Sousa chinensis): Unique features on the transplacental transfer
Bioaccumulation of legacy organic contaminants in pregnant Indo-Pacific humpback dolphins (Sousa chinensis): Unique features on the transplacental transfer
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怀孕的印度太平洋座头海豚（Sousa chinensis）体内遗留有机污染物的生物累积：经胎盘转移的独特特征
DOI：
10.1016/j.scitotenv.2021.147287
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发表时间：
2021
影响因子：
9.8
通讯作者：
Wu Yuping
中科院分区：
文献类型：
--
作者：
Zhang Xiyang;Zhan Fengping;Yu Ri-Qing;Sun Xian;Wu Yuping
有机污染物(OCs)在印度洋-太平洋座头海豚体内的胎盘迁移和同系物组成的研究很少。本文分析了珠江口三对多环芳烃(PAHs)、18种有机氯农药(OCPs)和28种多氯联苯(PCb)同系物在肌肉、肺、肝、肾和脂肪组织中的含量。对于多氯联苯，四、五、六和七氯苯同系物在所有被分析的样品中占主导地位。其中，在大多数海豚母婴组织样本中，六氯苯同系物的含量最高。成年女性解毒器官(肝脏和肾脏)中的多氯联苯和有机氯农药含量高于肌肉和肺部，而胎儿肌肉组织中的多氯联苯和有机氯农药含量一般高于肝脏和肾脏。四种组织中多环芳烃含量最高的是相对分子质量较低的多环芳烃，也是最易溶于水和生物可利用的。多氯联苯同系物的辛醇/水分配系数(LogKOW)与胎儿/母体比之间的负相关表明，多氯联苯的转移可能取决于它们的脂溶能力。低相对分子质量和低logKOW值的有机氯农药和多氯联苯更有可能在海豚的肝、肺、肾和肌肉组织中积聚。此外，低分子量和低logKOW值的OCS在胎儿的脂肪、肺和肝脏组织中比它们各自的母亲更集中。母胎配对中OCS的普遍存在强烈提示这些污染物可以通过胎盘在胎儿组织中分割。多环芳烃和多氯联苯的高迁移效率表明胎盘可能不是这些污染物的有效屏障。母海豚和胎儿海豚体内的多氯联苯水平都可能导致免疫抑制。
The placental transfer and congener composition of organic contaminants (OCs) in Indo-Pacific humpback dolphins have been little studied. In the present study, 16 polycyclic aromatic hydrocarbons (PAHs), 18 organochlorine pesticides (OCPs), and 28 polychlorinated biphenyl (PCB) congeners were analyzed in muscle, lung, liver, kidney, and blubber tissues from three mother–fetus pairs of this species stranded along the Pearl River Estuary, China. For PCBs, tetra-, penta-, hexa-, and hepta-chlorobenzene congeners were dominant in all the analyzed samples. Among them, hexachlorobenzene congeners showed the highest level in most dolphin mother-fetus tissue samples. The concentrations of PCBs and OCPs in adult females were higher in the detoxification organs (liver and kidneys) than in the muscles and lungs, whereas muscle tissues in fetuses generally exhibited higher PCBs and OCPs levels than the livers and kidneys. The most abundant PAHs in the four tissues were those with lower molecular weights, which were also the most water-soluble and bioavailable. Negative correlations between the octanol/water partition coefficients (logKOW) and the fetus/mother ratios for PCB congeners revealed that the transfer of PCBs may be determined by their lipid solubility. OCPs and PCBs with low molecular weights and low logKOWvalues would be more likely to accumulate in the dolphin liver, lung, kidney and muscle tissues. Furthermore, OCs with low molecular weights and low logKOWvalues were more concentrated in the fetal blubber, lung, and liver tissues than in their respective mothers. The ubiquitous existence of OCs in the mother–fetus pairs strongly suggested that these contaminants could pass through the placenta and partition in fetal tissue. The high transfer efficiency of PAHs and PCBs indicated that the placenta might not be an efficient barrier for these pollutants. PCBs levels in both mother and fetus dolphins could cause immunosuppression.