Hox clusters as models for vertebrate genome evolution
Hox clusters as models for vertebrate genome evolution
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DOI：
10.1016/j.tig.2005.06.004
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发表时间：
2005-08-01
影响因子：
11.4
通讯作者：
Meyer, A
中科院分区：
文献类型：
--
作者：
Hoegg, S;Meyer, A
脊椎动物谱系中，尤其是射线鳍鱼中，Hox 簇数量和基因组结构的惊人变化反映了重复和随后谱系特异性基因丢失的历史。最近对 Hox 簇中保守非编码序列 (CNS) 进化的研究有望揭示功能和表型多样化的有趣结果。
The surprising variation in the number of Hox clusters and the genomic architecture within vertebrate lineages, especially within the ray-finned fish, reflects a history of duplications and subsequent lineage-specific gene loss. Recent research on the evolution of conserved non-coding sequences (CNS) in Hox clusters promises to reveal interesting results for functional and phenotypic diversification.