Promoter elements, regulatory elements, and chromatin structure of the yeast his3 gene.
Promoter elements, regulatory elements, and chromatin structure of the yeast his3 gene.
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酵母 his3 基因的启动子元件、调节元件和染色质结构。
DOI：
10.1101/sqb.1983.047.01.104
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Struhl,K
中科院分区：
文献类型：
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作者：
Struhl,K
本文研究了面包酵母中一个简单的真核基因his3基因的结构与功能之间的关系。首先，我描述了基因实验，定义了his3表达所需的元件（启动子元件）以及作为细胞生理状态的功能负责调节表达水平的元件（调节元件）。其次，我讨论了这些遗传因素和his3基因的染色质结构之间的关系。
This paper deals with the relationship between the structure and function of a simple eukaryotic gene, the his3 gene of the baker's yeast Saccharomyces cerevisiae. First, I describe genetic experiments that define elements necessary for his3 expression (promoter elements) as well as elements responsible for regulating the level of expression as a function of the cell's physiological state (regulatory elements). Second, I discuss the relationship between these genetic elements and the chromatin structure of the his3 gene.