Maternal infection with toxoplasma gondii in pregnancy and the risk of hearing loss in the offspring
Maternal infection with toxoplasma gondii in pregnancy and the risk of hearing loss in the offspring
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DOI：
10.3109/14992020903214053
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发表时间：
2010-01-01
影响因子：
2.7
通讯作者：
Engdahl, Bo
中科院分区：
文献类型：
--
作者：
Austeng, Marit Erna;Eskild, Anne;Engdahl, Bo
本研究的目的是探讨孕妇感染弓形虫与其后代听力损失风险之间的关系。本研究包括1992-1994年在挪威出生的27727名儿童。孕妇弓形虫感染通过血清学检查确定，胎儿感染通过羊水寄生虫检测和/或出生后血清学检查确定。听力损失定义为平均听力损失>35 dB HL，在较好的汽车中，在500、1000和2000 Hz的纯音听阈上取平均值，通过与挪威儿童听力损失登记处的联系识别儿童。27727名儿童中有22名（0.08%）被诊断为听力损失。四十名女性患有原发性T。妊娠期弓形虫感染他们的后代都没有听力损失。T.妊娠前弓形虫感染和后代听力损失。因此，我们没有发现T。妊娠期弓形虫感染和后代听力损失。
The aim of this study was to investigate the association between maternal infection with Toxoplasma gondii IT. gondii) in pregnancy and subsequent risk of hearing loss in the offspring. The study included 27 727 children born in Norway 1992-1994, Maternal toxoplasma infection during pregnancy was ascertained by serological examination and fetal infection was ascertained by parasite detection in amniotic fluid and/or postnatal serological examination. Hearing loss was defined as mean hearing loss >35 dB HL, in the better car averaged over the pure-tone hearing thresholds at 500, 1000, and 2000 Hz, and the children were identified through linkage to the Norwegian Registry of Hearing Loss in Children. Twenty-two of the 27 727 children (0.08%) were diagnosed with hearing loss. Forty women had primary T. gondii infection in pregnancy. None of their offspring had hearing loss. There was also no association between T. gondii infection prior to pregnancy and hearing loss in the offspring. Hence, we did not find any association between T. gondii infection in pregnancy and hearing loss in the offspring.