A new epileptic seizure classification based exclusively on ictal semiology
A new epileptic seizure classification based exclusively on ictal semiology
复制标题
完全基于发作症状学的新癫痫发作分类
DOI：
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发表时间：
1999
影响因子：
3.5
通讯作者：
E. Wyllie
中科院分区：
文献类型：
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作者：
H. Lüders;Jayant Acharya;Christian Baumgartner;Selim R Benbadis;Andrew Bleasel;Richard C. Burgess;D. Dinner;A. Ebner;N. Foldvary;Eric B. Geller;H. Hamer;H. Holthausen;P. Kotagal;Harold H. Morris;H. Meencke;S. Noachtar;Felix Rosenow;A. Sakamoto;Bernhard J. Steinhoff;I. Tuxhorn;E. Wyllie
从历史上看，癫痫发作症状是癫痫综合征鉴别诊断的主要特征。随着临床脑电图的发展，电临床复合波的定义成为癫痫综合征，特别是局灶性癫痫综合征的重要工具。现代诊断技术的进步，特别是在神经影像学和分子生物学，现在允许更好地定义癫痫综合征。同时，详细的研究表明，癫痫发作或电临床综合征与癫痫综合征之间不一定存在一对一的关系。这些发展要求重新引入完全基于临床症状学的癫痫发作分类，类似于现代诊断方法引入之前神经科医生使用的癫痫发作分类。癫痫发作的这种分类应始终辅之以基于所有可用临床信息（临床病史、神经系统检查、发作症状学、EEG、解剖和功能神经影像学等）的癫痫综合征分类。这种方法更符合主流临床神经病学，并将避免目前癫痫发作分类（在国际癫痫发作分类中实际上是电临床综合征的分类）和癫痫综合征分类之间的混淆。
Historically, seizure semiology was the main feature in the differential diagnosis of epileptic syndromes. With the development of clinical EEG, the definition of electroclinical complexes became an essential tool to define epileptic syndromes, particularly focal epileptic syndromes. Modern advances in diagnostic technology, particularly in neuroimaging and molecular biology, now permit better definitions of epileptic syndromes. At the same time detailed studies showed that there does not necessarily exist a one‐to‐one relationship between epileptic seizures or electroclinical complexes and epileptic syndromes. These developments call for the reintroduction of an epileptic seizure classification based exclusively on clinical semiology, similar to the seizure classifications which were used by neurologists before the introduction of the modem diagnostic methods. This classification of epileptic seizures should always be complemented by an epileptic syndrome classification based on all the available clinical information (clinical history, neurological exam, ictal semiology, EEG, anatomical and functional neuroimaging, etc.). Such an approach is more consistent with mainstream clinical neurology and would avoid the current confusion between the classification of epileptic seizures (which in the International Seizure Classification is actually a classification of electroclinical complexes) and the classification of epileptic syndromes.