Waist-hip ratio is the dominant risk factor predicting cardiovascular death in Australia

Waist-hip ratio is the dominant risk factor predicting cardiovascular death in Australia
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DOI:
10.5694/j.1326-5377.2003.tb05704.x
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发表时间:
2003-12-01
影响因子:
11.4
通讯作者:
Bennett, SA
Bennett, SA
中科院分区:
医学2区
文献类型:
--
作者:
Welborn, TA;Dhaliwal, SS;Bennett, SA

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目的:为了评估肥胖的临床措施,他们的能力,以预测心血管疾病(CVD)和冠心病(CHD)死亡,在平行与传统的心血管risk factors.Design,参与者和设置:横断面分析的年龄和性别分层的样本9206名成年人年龄在20-69岁,从澳大利亚首府城市(1989年澳大利亚风险因素患病率调查)。记录血压、空腹血脂水平、吸烟史、心脏病或糖尿病史以及肥胖(通过体重指数(BMI)、腰围和腰臀比测量)。这些数据与国家死亡指数相关联,以确定截至2000年12月31日死亡的473名调查对象的死亡原因。主要结局指标:预测心血管死亡率和冠心病死亡率的危险因素的风险比。在可改变的风险因素中,肥胖(以腰臀比衡量)是一个占主导地位的、独立的、澳大利亚男女心血管疾病和冠心病死亡的预测变量。自我报告的心绞痛/心肌梗死在两种性别,吸烟的妇女,也是独立的风险factors.Conclusions:肥胖评估的腰臀比是一个更好的预测CVD和CHD死亡率比腰围,这反过来,是一个更好的预测比BMI。认识中心性肥胖在临床上是重要的,因为生活方式干预可能会提供显着的健康益处。
Objective: To evaluate clinical measures of obesity for their ability to predict death from cardiovascular disease (CVD) and coronary heart disease (CHD), in parallel with conventional cardiovascular risk factors.Design, participants and setting: Cross-sectional analysis of an age- and sex-stratified sample of 9206 adults aged 20-69 years from Australian capital cities (1989 Australian Risk Factor Prevalence Survey). Blood pressure, fasting serum lipid levels, smoking, history of heart disease or diabetes, and obesity as measured by body mass index (BMI), waist circumference and waist-hip ratio were recorded. These data were linked with the National Death Index to determine causes of death of the 473 survey subjects who had died to 31 December 2000.Main outcome measures: Hazard ratios for the risk factors predicting CVD mortality and CHD mortality.Results: Of the modifiable risk factors, obesity, as measured by waist-hip ratio, is a dominant, independent, predictive variable for CVD and CHD deaths in Australian men and women. Self-reported angina/myocardial infarction in both sexes, and cigarette smoking in women, are also independent risk factors.Conclusions: Obesity assessed by waist-hip ratio is a better predictor of CVD and CHD mortality than waist circumference, which, in turn, is a better predictor than BMI. The recognition of central obesity is clinically important, as lifestyle intervention is likely to provide significant health benefits.