Tasty THC: Promises and Challenges of Cannabis Edibles.
Tasty THC: Promises and Challenges of Cannabis Edibles.
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美味的THC：大麻食品的承诺和挑战。
DOI：
10.3768/rtipress.2016.op.0035.1611
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发表时间：
2016-11
期刊：
影响因子：
--
通讯作者：
Wiley JL
中科院分区：
文献类型：
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作者：
Barrus DG;Capogrossi KL;Cates SC;Gourdet CK;Peiper NC;Novak SP;Lefever TW;Wiley JL
含有大麻提取物的食品（食品）已成为娱乐和药用大麻合法化市场的一个受欢迎和有利可图的方面。食品中使用的大麻提取物的多种配方给决策者带来了独特的监管挑战。虽然食用通常被认为是一种安全，谨慎和有效的手段，可以在不暴露于大麻吸烟的潜在有害风险的情况下获得大麻的治疗和/或麻醉效果，但很少有研究评估摄入与其他大麻给药方法在治疗效果，主观效果和安全性方面的差异。吸食和吸入大麻提取物之间最显著的区别是吸食后药物作用的发生时间延迟。消费者通常不了解食用的这一方面，并且可能在药物生效之前消耗大于预期量的药物，通常导致严重的不良反应。本文是为受过教育的外行人和政策制定者撰写的，探讨了有关食用品的研究现状，强调了食用品给使用者和政策制定者带来的承诺和挑战，并描述了娱乐性大麻使用为法律的的四个州在监管食用品方面采取的方法。
Food products containing cannabis extract (edibles) have emerged as a popular and lucrative facet of the legalized market for both recreational and medicinal cannabis. The many formulations of cannabis extracts used in edibles present a unique regulatory challenge for policy makers. Though edibles are often considered a safe, discreet, and effective means of attaining the therapeutic and/or intoxicating effects of cannabis without exposure to the potentially harmful risks of cannabis smoking, little research has evaluated how ingestion differs from other methods of cannabis administration in terms of therapeutic efficacy, subjective effects, and safety. The most prominent difference between ingestion and inhalation of cannabis extracts is the delayed onset of drug effect with ingestion. Consumers often do not understand this aspect of edible use and may consume a greater than intended amount of drug before the drug has taken effect, often resulting in profoundly adverse effects. Written for the educated layperson and for policy makers, this paper explores the current state of research regarding edibles, highlighting the promises and challenges that edibles present to both users and policy makers, and describes the approaches that four states in which recreational cannabis use is legal have taken regarding regulating edibles.