The record of horizontal gene transfer in Salmonella

The record of horizontal gene transfer in Salmonella
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DOI:
10.1016/s0966-842x(97)01082-2
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发表时间:
1997-08-01
影响因子:
15.9
通讯作者:
Baumler, AJ
Baumler, AJ
中科院分区:
生物学1区
文献类型:
--
作者:
Baumler, AJ

文献摘要

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沙门氏菌毒力的进化是由水平基因转移驱动的。这就产生了高度灵活的病原体,它们能够在新的生态位中定居并扩大其宿主范围。追踪水平基因转移的记录可以为有助于新致病型形成的毒力因子提供线索。
The evolution of virulence in Salmonella is driven by horizontal gene transfer. This has given rise to highly flexible pathogens that are able to colonize new niches and extend their host range. Tracing the record of horizontal gene transfer can provide clues to the virulence factors that contribute to the formation of new pathovars.