Harnessing SeN to develop novel fluorescent probes for visualizing the variation of endogenous hypobromous acid (HOBr) during the administration of an immunotherapeutic agent.
Harnessing SeN to develop novel fluorescent probes for visualizing the variation of endogenous hypobromous acid (HOBr) during the administration of an immunotherapeutic agent.
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DOI：
10.1039/d1cc04832e
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发表时间：
2021-11
影响因子：
4.9
通讯作者：
J. Zhang;Kaiqiang Liu;Jingwen Li;Yingying Xie;Yong Li;Xu Wang;Xilei Xie;Xiaoyun Jiao;
中科院分区：
文献类型：
--
作者：
J. Zhang;Kaiqiang Liu;Jingwen Li;Yingying Xie;Yong Li;Xu Wang;Xilei Xie;Xiaoyun Jiao;
利用硒代氮的形成，建立了检测和显示活细胞内源性次溴酸（HOBr）的ABT-Se和NDI-Se。具体地，在施用免疫抑制剂期间通过NDI-Se监测HOBr的上调。
By means of the formation of SeN, the ABT-Se and NDI-Se were developed to detect and visualize endogenous hypobromous acid (HOBr) in live cells. Specifically, the upregulation of HOBr was monitored by NDI-Se during the administration of an immunotherapeutic agent.