Predictors of chronic breathlessness: a large population study
Predictors of chronic breathlessness: a large population study
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DOI：
10.1186/1471-2458-11-33
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发表时间：
2011-01-12
影响因子：
4.5
通讯作者：
Currow, David C.
中科院分区：
文献类型：
--
作者：
Bowden, Jacqueline A.;To, Timothy H. M.;Currow, David C.
背景资料：呼吸困难对我们的社区造成重大负担，但可能影响它的潜在社会人口和生活方式因素尚未得到很好的量化。本研究的目的是定义这些慢性呼吸困难的预测在人口level.Methods：数据收集从成年南澳大利亚人在2007年和2008年（n = 5331）的一部分，面对面的，横截面，整个人口，多阶段，系统的区域抽样人口健康调查。在逻辑回归模型中，主要结果变量是呼吸困难。调查的生活方式因素包括吸烟史、无烟住房、体力活动水平和身体质量指数（肥胖）。结果：参与率为64.1%，11.1%的人（15.0%的人年龄>= 50岁）有慢性呼吸困难，限制了体力活动。在整个人群中，与慢性呼吸困难显著的双变量相关性（仅≥ 50）包括：年龄增加;女性;分居/离婚/丧偶;社会劣势;吸烟状况;没有无烟家庭的人;体力活动水平低;肥胖。在调整了年龄、婚姻状况（p < 0.001）、体力活动（p <0.001）、肥胖（p <0.001）、性别（p < 0.05）和社会劣势（p < 0.05）的多变量分析中，仍然是重要因素。吸烟史是不是一个显着的贡献者的model.Conclusions：有潜在的好处，在解决可逆的生活方式呼吸困难的原因，包括高体重指数（肥胖）和低水平的体力活动，以减少慢性呼吸困难的患病率。慢性呼吸困难的临床干预研究应考虑按体重指数分层。
Background: Breathlessness causes significant burden in our community but the underlying socio-demographic and lifestyle factors that may influence it are not well quantified. This study aims to define these predictors of chronic breathlessness at a population level.Methods: Data were collected from adult South Australians in 2007 and 2008 (n = 5331) as part of a face-to-face, cross-sectional, whole-of-population, multi-stage, systematic area sampling population health survey. The main outcome variable was breathlessness in logistic regression models. Lifestyle factors examined included smoking history, smoke-free housing, level of physical activity and body mass index (obesity).Results: The participation rate was 64.1%, and 11.1% of individuals (15.0% if aged >= 50 years) chronically had breathlessness that limited exertion. Significant bivariate associations with chronic breathlessness for the whole population and only those = 50 included: increasing age; female gender; being separated/divorced/widowed; social disadvantage; smoking status; those without a smoke-free home; low levels of physical activity; and obesity. In multi-variate analyses adjusted for age, marital status (p < 0.001), physical activity (p < 0.001), obesity (p < 0.001), gender (p < 0.05) and social disadvantage (p < 0.05) remained significant factors. Smoking history was not a significant contributor to the model.Conclusions: There is potential benefit in addressing reversible lifestyle causes of breathlessness including high body mass index (obesity) and low levels of physical activity in order to decrease the prevalence of chronic breathlessness. Clinical intervention studies for chronic breathlessness should consider stratification by body mass index.