Microstructure, mineral and mechanical properties of teleost intermuscular bones
Microstructure, mineral and mechanical properties of teleost intermuscular bones
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DOI：
10.1016/j.jbiomech.2019.07.009
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发表时间：
2019-09-20
影响因子：
2.4
通讯作者：
Berteau, J. P.
中科院分区：
文献类型：
--
作者：
Fiedler, I. A. K.;Zeveleva, S.;Berteau, J. P.
在一些科学界，人们对了解硬骨鱼骨骼生物力学的兴趣日益增加，例如将其作为具有特定结构 - 功能关系的有趣生物材料。此前有研究表明硬骨鱼的肌间骨在肌肉和骨骼之间的机械力传递中起作用，但其生物力学特性尚未得到充分描述。在此，我们对北大西洋鲱鱼的肌间骨（IBs）进行了研究，包括其结构和微观结构、与矿物质相关的特性以及微观力学拉伸特性。共研究了来自18条鱼的115根肌间骨。其中一组肌间骨，包含来自2条较小的鱼的20根骨头和来自3条较大的鱼的23根骨头，用于力学测试、广角X射线散射和扫描电子显微镜观察。另一组包含来自7条较小的鱼的36根骨头和来自6条较大的鱼的36根骨头，用于显微CT检测。结果显示肌间骨具有一些令人惊讶的特性：（i）与哺乳动物的骨骼相比，肌间骨具有更高的延展性、更低的杨氏模量，但强度和组织矿物质密度（TMD）相似；（ii）小鱼的肌间骨杨氏模量比大鱼的鱼骨高49%，而它们的组织矿物质密度无统计学差异，并且大鱼骨的晶体长度高8%。我们的研究结果表明，硬骨鱼的肌间骨呈现出一种软硬组织混合的特性，这与其他骨骼类型不同，这可能与其从矿化肌腱进化而来有关。这项研究提供了有关硬骨鱼骨骼生物力学和微观结构特性的新数据。（C）2019年由爱思唯尔有限公司出版
There is an increasing interest in understanding teleost bone biomechanics in several scientific communities, for instance as interesting biomaterials with specific structure-function relationships. Intermuscular bones of teleost fish have previously been described to play a role in the mechanical force transmission between muscle and bone, but their biomechanical properties are not yet fully described. Here, we have investigated intermuscular bones (IBs) of the North Atlantic Herring with regard to their structure and micro-architecture, mineral-related properties, and micro-mechanical tensile properties. A total of 115 IBs from 18 fish were investigated. One cohort of IBs, containing 20 bones from 2 smaller fish and 23 bones of 3 larger fish, was used for mechanical testing, wide-angle X-ray scattering, and scanning electron microscopy. Another cohort, containing 36 bones from 7 smaller fish and 36 bones from 6 larger fish, was used for microCT. Results show some astonishing properties of the IBs: (i) IBs present higher ductility, lower Young's modulus but similar strength and TMD (Tissue Mineral Density) compared to mammalian bone, and (ii) IBs from small fish were 49% higher in Young's modulus than fish bones from larger fish while their TMD was not statistically different and crystal length was 8% higher in large fish bones. Our results revealed that teleost IB presents a hybrid nature of soft and hard tissue that differs from other bone types, which might be associated with their evolution from mineralized tendons. This study provides new data regarding teleost fish bone biomechanical and micro-structural properties. (C) 2019 Published by Elsevier Ltd.