BIAXIAL ANISOTROPY OF DOG CAROTID-ARTERY - ESTIMATION OF CIRCUMFERENTIAL ELASTIC-MODULUS
BIAXIAL ANISOTROPY OF DOG CAROTID-ARTERY - ESTIMATION OF CIRCUMFERENTIAL ELASTIC-MODULUS
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DOI：
10.1016/0021-9290(86)90011-4
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发表时间：
1986-01-01
影响因子：
2.4
通讯作者：
DOBRIN, PB
中科院分区：
文献类型：
--
作者：
DOBRIN, PB
实验进行了研究双轴各向异性松弛犬颈动脉受到广泛的纵向长度和跨壁压力。为了涵盖原位发生的血管长度的范围，在相对于收缩的血管长度的20%、40%、60%和80%延伸下研究了120条颈动脉。这些研究以系统随机顺序进行。在每个长度处，血管逐步加压至200 mmHg跨壁压，或直至牵引力降至零。结果表明，纵向拉伸显著提高了纤维的纵向弹性模量，但对周向弹性模量影响不大。在生理压力下，血管在约70%的纵向延伸处几乎是各向同性的，但在较短的长度处是各向异性的。通过许多简化方法对各向异性周向模量的估计表明，使用“压力弹性模量”（Ep）低估了80%的各向异性模量，但非常一致。因此，当适当校正时，Ep可以用于可靠地估计颈动脉在宽范围的压力和血管长度上的各向异性模量。
Experiments were performed to study biaxial anisotropy in relaxed canine carotid arteries subjected to a wide range of longitudinal lengths and transmural pressures. In order to encompass the range of vessel lengths which occurs in situ, 120 carotid arteries were studied at 20%, 40%, 60% and 80% extension relative to retracted vessel length. These studies were performed in systematically randomized order. At each length, the vessels were pressurized in steps up to 200 mmHg transmural pressure, or until the traction force fell to zero. Results showed that longitudinal extension markedly increased the longitudinal elastic modulus, but had only a slight effect on the circumferential modulus. At physiological pressures, the vessels were nearly isotropic at about 70% longitudinal extension, but were anisotropic at shorter lengths. Estimates of the anisotropic circumferential modulus by a number of simplified methods revealed that use of a ''pressure-elastic modulus'' (Ep) underestimated the anisotropic modulus by 80%, but was extremely consistent. Therefore when suitably corrected, Ep could be used to reliably estimate the anisotropic modulus of carotid arteries over a wide range of pressures and vessel lengths.