MR imaging of rheumatoid hand lesions: comparison with conventional radiology in 31 patients.
MR imaging of rheumatoid hand lesions: comparison with conventional radiology in 31 patients.
复制标题
类风湿手部病变的 MR 成像：31 例患者与传统放射学的比较。
DOI：
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发表时间：
1992
影响因子：
3.7
通讯作者：
E. Nigris
中科院分区：
文献类型：
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作者：
A. Corvetta;Andrea Giovagnoni;S. Baldelli;P. Ercolant;Giovanni Pomponio;M. Luchetti;N. Rinaldi;E. Nigris
本研究的目的是评价磁共振成像（MRI）诊断类风湿关节炎（RA）的准确性，通过比较MRI与传统的放射学（CR）的结果，并将这些结果与疾病的临床和血清学资料。用Magnetom 1.0T断层扫描仪对31例（女24例，男7例）典型类风湿关节炎患者的手进行了研究。所有患者均获得冠状位、轴位和/或矢状位SE T1和GE（FLASH 2D FL：70度-15度）图像。此外，在7例患者中，MRI研究是在静脉注射Gd DTPA造影剂（0.2 mM/kg）后进行的。10名健康志愿者作为对照。在所有患者中进行常规放射学研究以及临床和血清学调查。两名设盲观察员评估MRI和CR结果，并检查15个基本病理病变，为每位患者分配MRI和CR评分。MRI在检测类风湿软组织改变和微小骨骼病变方面比CR提供了更高的准确性，而对于严重骨骼病变则相反。MRI/CR结果与临床和血清学数据之间没有相关性。本研究表明，MRI和CR在评估RA的解剖学变化方面是互补的技术。
The purpose of this study was to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in rheumatoid arthritis (RA) by comparing MRI with conventional radiology (CR) findings and by correlating these findings with the clinical and serological profile of the disease. The hands of 31 patients (24 females, 7 males) affected by classical RA were studied using a Magnetom 1.0 T tomograph. Coronal, axial, and/or sagittal SE T1 and GE (FLASH 2D FL: 70 degrees-15 degrees) images were obtained in all patients. Moreover, in 7 patients the MRI study was performed after i.v. injection of Gd DTPA contrast medium (0.2 mM/kg). Ten healthy volunteers were also studied as controls. In all patients a conventional radiological study was performed as well as a clinical and serological investigation. Two blinded observers evaluated the MRI and CR findings and checked 15 elementary pathological lesions, assigning an MRI and a CR score to each patient. MRI provided higher accuracy than CR in detecting rheumatoid soft tissue changes and minimal skeletal lesions, while the opposite was true for severe skeletal lesions. No correlations emerged between the MRI/CR findings and clinical and serological data. This study suggests that MRI and CR are complementary techniques in the evaluation of the anatomical changes in RA.