Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation on Depression and Cognition of Patients with Traumatic Brain Injury: A Randomized Controlled Trial
Effect of Low Frequency Repetitive Transcranial Magnetic Stimulation on Depression and Cognition of Patients with Traumatic Brain Injury: A Randomized Controlled Trial
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DOI：
10.12659/msm.911385
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发表时间：
2018-12-04
影响因子：
3.1
通讯作者：
Kim, Myoung-Kwon
中科院分区：
文献类型：
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作者：
Lee, Si A.;Kim, Myoung-Kwon
背景资料：本研究旨在探讨低频重复经颅磁刺激（rTMS）对创伤性脑损伤患者抑郁和认知功能的影响。材料/方法：将13例创伤性脑损伤患者分为实验组（n=7）和对照组（n=6）。实验组接受rTMS，每周5天，每次30分钟，持续2周;对照组接受假rTMS。采用蒙哥马利-艾斯伯格抑郁量表（MADRS）评定抑郁症状，采用连线测验（TMT）和Stroop色词测验（SCWT）评定认知功能。结果：实验组干预后MADRS、TMT和SCWT均明显下降（P
Background: This study was conducted to investigate the effects of low frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex on depression and cognition in patients with traumatic brain injury.Material/Methods: To accomplish this, 13 patients who were diagnosed with traumatic brain injury were divided into an experimental group (n=7) and a control group (n=6). The experimental group received rTMS during a 30-minute session 5 days per week for 2 weeks; the control group received sham rTMS. The patients were then evaluated for depression using the Montgomery-Asberg Depression Rating Scale (MADRS) and for cognitive function using the Trail Making Test (TMT) and the Stroop Color Word Test (SCWT).Results: A significant decrease in MADRS, TMT, and SCWT was observed after the intervention in the experimental group (P