Racial disparities in survival among patients with germ cell tumors of the ovary - United States

Racial disparities in survival among patients with germ cell tumors of the ovary - United States
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DOI:
10.1016/j.ygyno.2009.05.039
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发表时间:
2009-09-01
影响因子:
4.7
通讯作者:
Morris, Robert T.
Morris, Robert T.
中科院分区:
医学2区
文献类型:
--
作者:
Bryant, Christopher S.;Kumar, Sanjeev;Morris, Robert T.

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Objective(s). To compare the survival of African American (AA) and white (W) patients with malignant germ cell tumors of the ovary (OGCT).Methods. Patients with a diagnosis of OGCT were identified from Surveillance, Epidemiology, and End Results Program (SEER) from 1988 to 2004, and were divided into African American (AA) and white (W) subgroups. Only surgically treated patients were included. Histology was grouped into dysgerminoma (D), malignant teratoma (MT), and mixed germ cell tumors with pure non-dysgerminoma cell tumors (MGCT/PNDCT). Statistical analysis using Chi-square, Fisher's Exact Test, Kaplan-Meier survival methods, and Cox regression proportional hazards were performed.Results. In 1110 patients with OGCT, 970 (87.4%) were Wand 140 (12.6%) were AA. MGCT/PNDCT histology was equally represented in AA and W. However, W were twice as likely to present with D (W 34% vs. AA 16%, p