LOCALIZATION OF OCULAR ADRENERGIC NERVES AND BARRIER MECHANISMS IN SOME MAMMALS
LOCALIZATION OF OCULAR ADRENERGIC NERVES AND BARRIER MECHANISMS IN SOME MAMMALS
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一些哺乳动物的眼肾上腺素神经和屏障机制的定位
DOI：
10.1111/j.1755-3768.1966.tb05508.x
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发表时间：
1966
影响因子：
3.4
通讯作者：
B. Ehinger
中科院分区：
文献类型：
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作者：
B. Ehinger
眼肾上腺素能神经的分布在不同种属之间存在着明显的差异。G.在房角或瞳孔括约肌中（Ehinger 1964 B和1965 a c）促使人们对各种哺乳动物的眼神经支配进行进一步研究。除了他们的一般利益，这样的调查可以预期揭示一些不一致的生理和药理学结果。肾上腺素能神经对儿茶酚胺（CA）和多巴的摄取可以用法尔克和希拉尔普的荧光技术来观察（参见图1）。法尔克和Owman 1965 B，Malmfors 1965）。因此，可以证明正常情况下不显示任何荧光但具有这种摄取机制的神经。先前的研究在某些物种中未能显示肾上腺素能纤维存在于某些部位，而这些部位可能存在于其他物种中（Ehinger 1964 B，1966 a-c）。为了能够合理地说明肾上腺素能纤维的缺失，有必要进行旨在显示神经具有摄取和储存I-DOPA或DA的能力的实验。
The fact that pronounced differences exist between various species in the distribution of ocular adrenergic nerves, e. g. in the chamber angle or in the sphincter pupillae (Ehinger 1964 b and 1965 a c) has prompted further studies on the ocular innervation of various mammals. In addition to their general interest, such investigations can be expected to shed light on some discrepant physiological and pharmacological results. The uptake of catecholamines (CA) and DOPA into adrenergic nerves can be visualized with the fluorescence technique of Falck and Hillarp (cf. Falck and Owman 1965 b, Malmfors 1965). Thus, nerves which do not normally display any fluorescence but possess such an uptake mechanism may be demonstrated. Previous investigations have in certain species failed to show adrenergic fibres a t some sites were they could be expected, and where they are to be found in other species (Ehinger 1964 b, 1966 a-c). Experiments designed to show nerves with the ability to take up and to store I-DOPA or DA are necessary in order to be able to state any absence of adrenergic fibres with reasonable occuracy.