The course of distress in women at increased risk of breast and ovarian cancer due to an (identified) genetic susceptibility who opt for prophylactic mastectomy and/or salpingo-oophorectomy
The course of distress in women at increased risk of breast and ovarian cancer due to an (identified) genetic susceptibility who opt for prophylactic mastectomy and/or salpingo-oophorectomy
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DOI：
10.1016/j.ejca.2006.09.009
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发表时间：
2007-01-01
影响因子：
8.4
通讯作者：
Tibben, A.
中科院分区：
文献类型：
--
作者：
Bresser, P. J. C.;Seynaeve, C.;Tibben, A.
对78名妇女在预防性乳房切除术（PM）和/或预防性输卵管切除术（PSO）前后的心理困扰水平和过程进行了研究。采用医院焦虑抑郁量表（HADS）测量患者的一般痛苦，采用事件影响量表（IES）测量癌症相关痛苦。测量时刻为基线（预防性手术前2 - 4周）、术后6个月和12个月。PM后，焦虑和癌症相关的痛苦显着减少，而PSO后没有观察到显着变化的痛苦评分。在预防性手术后一年，大量的妇女仍然在临床相关的增加水平的癌症相关的痛苦和anxiety. We的结论是，大多数妇女可以接受PM和/或PSO没有开发重大的情绪困扰。需要进行更多的研究，以进一步确定手术后继续具有临床相关评分增加的女性的特征，以便为她们提供额外的咨询。(c)2006爱思唯尔有限公司保留所有权利。
The levels and course of psychological distress before and after prophylactic mastectomy (PM) and/or prophylactic salpingo-cophorectomy (PSO) were studied in a group of 78 women. General distress was measured through the hospital anxiety and depression scale (HADS), cancer-related distress using the impact of events scale (IES). Measurement moments were baseline (2-4 weeks prior to prophylactic surgery), and 6 and 12 months post-surgery. After PM, anxiety and cancer-related distress were significantly reduced, whereas no significant changes in distress scores were observed after PSO. At one year after prophylactic surgery; a substantial amount of women remained at clinically relevant increased levels of cancer-related distress and anxiety.We conclude that most women can undergo PM and/or PSO without developing major emotional distress. More research is needed to further define the characteristics of the women who continue to have clinically relevant increased scores after surgery, in order to offer them additional counselling. (c) 2006 Elsevier Ltd. All rights reserved.