Antioxidant Activity of Bacteria Associated with the Marine Sponge Tedania anhelans
Antioxidant Activity of Bacteria Associated with the Marine Sponge Tedania anhelans
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DOI：
10.1007/s12088-014-0490-8
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发表时间：
2015-03-01
影响因子：
3
通讯作者：
Nithyanand, Paramasivam
中科院分区：
文献类型：
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作者：
Balakrishnan, Dhivya;Bibiana, Arulanandu Sabreen;Nithyanand, Paramasivam
海洋环境已被证明是抗氧化化合物的一个有前途的来源，从海绵、海藻和海洋微生物中提取的一些新分子具有良好的抗氧化性能。虽然在世界范围内对黑helans的次生代谢产物进行了探索，但对其相关细菌抗氧化性能的研究非常有限。在本研究中，分离了几种与genbank中最接近的匹配株相似度仅为97%的芽孢杆菌，并发现它们具有清除自由基的活性。在碱性条件下抗氧化活性稳定，GC-MS谱分析表明乙酸乙酯提取物中存在多种抗氧化化合物。据我们所知，目前的研究是第一次报道与抗氧化菌相关的细菌。
The marine environment has proved to be a promising source of antioxidant compounds as several novel molecules that are derived from sponges, sea weed and marine microbes exhibit good antioxidant properties. Though the secondary metabolites of T. anhelans are being explored world wide, studies related with antioxidant property of its associated bacteria are very limited. In the present study, several Bacillus sp. with just 97 % similarity with its closest match in Gen Bank were isolated, and found to show free radical scavenging activity. The anti-oxidant activity was stable at alkaline pH and the GC-MS spectra showed the presence of several anti-oxidant compounds in the ethyl acetate extract of the bacterial cultures. To the best of our knowledge the present study is first of its kind to report about bacteria associated with the T. anhelans with antioxidant activity.