Treatment of Ulcerative Colitis in the Elderly
Treatment of Ulcerative Colitis in the Elderly
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DOI：
10.1159/000228569
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发表时间：
2009-01-01
影响因子：
2.3
通讯作者：
Binion, David G.
中科院分区：
文献类型：
--
作者：
Ananthakrishnan, Ashwin N.;Binion, David G.
溃疡性结肠炎（UC）具有双峰年龄分布，大多数患者在生命的第二和第四十年之间被诊断出来。然而，第二个诊断高峰出现在老年患者中，估计有15%的患者在65岁以后出现。照顾老年UC患者，无论是出现较晚的生活或谁携带炎症性肠病（IBD）诊断了几十年可能会带来额外的挑战，在管理。最近使用美国全国管理数据库的研究表明，老年IBD患者的医院预后较差。UC和克罗恩病的这种模式表明，与年轻IBD患者相比，血管并发症（如静脉血栓形成）的发生率增加，术后结果更差，并发症和延长临床病程的发生率增加。本文概述了老年UC患者的护理，包括诊断和治疗方面的考虑。版权所有(C) 2009 S. Karger AG，巴塞尔
Ulcerative colitis (UC) has a bimodal age distribution, with the majority of patients being diagnosed between the second and fourth decades of life. However, a second peak in diagnosis occurs in older patients and an estimated 15% of patients present after age 65. Caring for older UC patients who have either presented later in life or who have carried an inflammatory bowel disease (IBD) diagnosis for multiple decades may pose additional challenges in management. Recent studies using nationwide administrative databases from the USA have demonstrated that older IBD patients are challenged by worse hospital outcomes. This pattern, seen for both UC and Crohn's disease, demonstrated increased rates of vascular complications (i.e. venous thrombosis), worse post-operative outcomes and increased rates of complicated and prolonged clinical courses compared to younger IBD patients. This article provides an overview of caring for elderly patients with UC, including diagnostic and therapeutic considerations. Copyright (C) 2009 S. Karger AG, Basel