Screening for posttraumatic stress disorder in ARDS survivors: validation of the Impact of Event Scale-6 (IES-6)
Screening for posttraumatic stress disorder in ARDS survivors: validation of the Impact of Event Scale-6 (IES-6)
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DOI：
10.1186/s13054-019-2553-z
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发表时间：
2019-08-07
期刊：
影响因子：
15.1
通讯作者：
Neufeld, Karin J.
中科院分区：
文献类型：
--
作者：
Hosey, Megan M.;Leoutsakos, Jeannie-Marie S.;Neufeld, Karin J.
背景 创伤后应激障碍 (PTSD) 症状在急性呼吸窘迫综合征 (ARDS) 幸存者中很常见。临床和研究目的需要简单的筛选仪器。我们评估了事件影响量表 6（IES-6；6 项）的内部一致性、外部结构和标准有效性，与原始事件影响量表修订版（IES-R；22 项）和临床医生管理的 PTSD 量表 (CAPS) 参考标准评估 ARDS 幸存者进行比较。方法 本研究是对 ARDS 幸存者进行的两项独立的多中心前瞻性研究的二次分析。评估了内部一致性、外部结构和标准有效性的衡量标准。结果 总共评估了 1001 名 ARDS 幸存者（51% 为女性，76% 为白人，平均 (SD) 年龄 49 (14) 岁）。 IES-6 证明了 ARDS 后长达 5 年的多个时间点的内部一致性（Cronbach's alpha = 0.96；95% 置信区间 (CI) 0.94 至 0.97）。 IES-6 与相关结构（例如，焦虑和抑郁；|r| = 0.32 至 0.52）表现出较强的相关性，而与不相关结构（例如，身体功能和医疗保健利用措施（|r| = 0.02 至 0.27））的相关性较弱。在 60 名参与者的子样本中，对 PTSD 的 CAPS 诊断进行的标准有效性评估得出了受试者工作特征曲线下的面积 (95% CI) 为 0.93 (0.86, 1.00)，IES-6 截止分数为 1.75，敏感性为 0.88，特异性为 0.85。结论 IES-6 对于 ARDS 幸存者的 PTSD 筛查是可靠且有效的，并且可能在临床和研究环境中有用。
Background Posttraumatic stress disorder (PTSD) symptoms are common in acute respiratory distress syndrome (ARDS) survivors. Brief screening instruments are needed for clinical and research purposes. We evaluated internal consistency, external construct, and criterion validity of the Impact of Event Scale-6 (IES-6; 6 items) compared to the original Impact of Event Scale-Revised (IES-R; 22 items) and to the Clinician Administered PTSD Scale (CAPS) reference standard evaluation in ARDS survivors. Methods This study is a secondary analysis from two independent multi-site, prospective studies of ARDS survivors. Measures of internal consistency, and external construct and criterion validity were evaluated. Results A total of 1001 ARDS survivors (51% female, 76% white, mean (SD) age 49 (14) years) were evaluated. The IES-6 demonstrated internal consistency over multiple time points up to 5 years after ARDS (Cronbach's alpha = 0.96; 95% confidence interval (CI) 0.94 to 0.97). The IES-6 demonstrated stronger correlations with related constructs (e.g., anxiety and depression; |r| = 0.32 to 0.52) and weaker correlations with unrelated constructs (e.g., physical function and healthcare utilization measures (|r| = 0.02 to 0.27). Criterion validity evaluation with the CAPS diagnosis of PTSD in a subsample of 60 participants yielded an area under receiver operating characteristic curve (95% CI) of 0.93 (0.86, 1.00), with an IES-6 cutoff score of 1.75 yielding 0.88 sensitivity and 0.85 specificity. Conclusions The IES-6 is reliable and valid for screening for PTSD in ARDS survivors and may be useful in clinical and research settings.