Anti-Markovnikov Addition of Anilines to Aliphatic Terminal Alkynes Catalyzed by an 8-Quinolinolato Rhodium Complex
Anti-Markovnikov Addition of Anilines to Aliphatic Terminal Alkynes Catalyzed by an 8-Quinolinolato Rhodium Complex
复制标题
8-喹啉铑络合物催化苯胺与脂肪族末端炔烃的反马可夫尼科夫加成
DOI：
10.1002/hlca.202100125
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
F. Kakiuchi
中科院分区：
文献类型：
--
作者：
Y. Morimoto;T. Kochi;F. Kakiuchi
使用8-羟基喹啉合铑/膦催化剂体系进行苯胺与脂肪族末端炔的反马尔可夫尼科夫加成。在催化剂体系中使用强有机碱1，1，3，3-四甲基胍使得能够形成醛亚胺产物。具有包括极性基团如酚羟基的各种官能团的底物适用于加氢胺化。
Anti‐Markovnikovaddition of anilines to aliphatic terminal alkynes proceeded using an 8‐quinolinolato rhodium/phosphine catalyst system. The use of a strong organic base, 1,1,3,3,–tetramethylguanidine, in the catalyst system enabled the formation of the aldimine products. Substrates with various functional groups including polar groups such as a phenolic hydroxy group are applicable to the hydroamination.