Phytochemistry and pharmacology of berberis species.
Phytochemistry and pharmacology of berberis species.
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DOI：
10.4103/0973-7847.125517
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发表时间：
2014-01
期刊：
影响因子：
--
通讯作者：
Kurepaz-Mahmoodabadi M
中科院分区：
文献类型：
--
作者：
Mokhber-Dezfuli N;Saeidnia S;Gohari AR;Kurepaz-Mahmoodabadi M
小檗属（小檗科）在全世界约有 500 种，其中一些在伊朗东北部地区广泛种植。该属由带刺的落叶常绿灌木组成，其特征是黄色的木材和花朵。南呼罗珊省无籽伏牛花的种植历史可以追溯到两百多年前。这些植物所有部分的药用特性均已被报道，包括：抗菌、止吐、解热、抗氧化、抗炎、抗心律失常、镇静、抗胆碱能、利胆、抗利什曼病和抗疟疾。在各种小檗中发现的主要化合物是小檗碱和小檗胺。该属各种物种的植物化学分析表明存在生物碱、单宁、酚类化合物、甾醇和三萜。虽然有一些关于小檗属（作为应用最多的物种）的综述文章，但没有对小檗属其他知名物种的植物化学和药理活性的综述。因此，本综述主要集中于该属不同物种的丰富的次生代谢产物和相当多的药理和生物活性，以及植物学和栽培的简明故事。
The genus Berberis (Berberidaceae) includes about 500 species worldwide, some of which are widely cultivated in the north-eastern regions of Iran. This genus consists of spiny deciduous evergreen shrubs, characterized by yellow wood and flowers. The cultivation of seedless barberry in South Khorasan goes back to two hundred years ago. Medicinal properties for all parts of these plants have been reported, including: Antimicrobial, antiemetic, antipyretic, antioxidant, anti-inflammatory, anti-arrhythmic, sedative, anti-cholinergic, cholagogic, anti-leishmaniasis, and anti-malaria. The main compounds found in various species of Berberis, are berberine and berbamine. Phytochemical analysis of various species of this genus revealed the presence of alkaloids, tannins, phenolic compounds, sterols and triterpenes. Although there are some review articles on Berberis vulgaris (as the most applied species), there is no review on the phytochemical and pharmacological activities of other well-known species of the genus Berberis. For this reason, the present review mainly focused on the diverse secondary metabolites of various species of this genus and the considerable pharmacological and biological activities together with a concise story of the botany and cultivation.