The Impact of Obesity on Allograft Failure After Kidney Transplantation: A Competing Risks Analysis
The Impact of Obesity on Allograft Failure After Kidney Transplantation: A Competing Risks Analysis
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DOI：
10.1097/tp.0000000000000983
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发表时间：
2016-09-01
期刊：
影响因子：
6.2
通讯作者：
Lentine, Krista L.
中科院分区：
文献类型：
--
作者：
Naik, Abhijit S.;Sakhuja, Ankit;Lentine, Krista L.
移植前体重指数（BMI）对肾移植术后长期移植物结局的影响仍存在争议。传统的方法使用Kaplan-Meier方法来计算死亡审查的同种异体移植失败的累积风险可能会高估失败的风险，特别是当竞争失败risks are present.Method的回顾性队列的成人首次肾移植受者来自器官采购和移植网络数据库（2001年至2009年）。根据世界卫生组织的肥胖分类，BMI被分类为：小于18.5、18.5至18.5。
Background The impact of pretransplant body mass index (BMI) on long-term allograft outcomes after kidney transplantation remains controversial. The conventional approach of using Kaplan-Meier method to calculate the cumulative risk of death-censored allograft failure may overestimate the risk of failure especially when competing failure risks are present.Method A retrospective cohort of adult first-time kidney transplant recipients was drawn from the Organ Procurement and Transplantation Network database (2001 to 2009). Based on World Health Organization obesity classification, BMI was categorized as: less than 18.5, 18.5 to