Haloperidol produces hypothermic effects in rats
Haloperidol produces hypothermic effects in rats
复制标题
氟哌啶醇对大鼠产生低温作用
DOI：
10.1007/bf01962790
复制
发表时间：
1979
期刊：
影响因子：
--
通讯作者：
Y. Chern
中科院分区：
文献类型：
--
作者：
M. Lin;H. S. Wang;Zyx Wang;Y. Chern
无论是氟哌啶醇还是氯丙嗪，在寒冷（8° C）和室温（22°C）下腹腔内给药均会导致体温降低。低温是由代谢产热减少和尾部和足部皮肤温度增加引起的。然而，在较高的温度（29°C）下，直肠温度和其他体温调节反应没有变化。
Intraperitoneal administration of either haloperidol or chlorpromazine produced hypothermia both in the cold (8° C) and at room temperature (22°C). The hypothermia was brought about both by a decrease in metabolic heat production and an increase in the cutaneous temperature of tail and foot skin. However, at a higher temperature (29°C), there were no changes in rectal temperature and other thermoregulatory responses.