Optical Techniques in Optogenetics.

Optical Techniques in Optogenetics.
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DOI:
10.1080/09500340.2015.1010620
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发表时间:
2015
影响因子:
1.3
通讯作者:
Lakshminarayananan V
Lakshminarayananan V
中科院分区:
物理与天体物理4区
文献类型:
--
作者:
Mohanty SK;Lakshminarayananan V

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Optogenetics is an innovative technique for optical control of cells. This field has exploded over the past decade or so and has given rise to great advances in neuroscience. A variety of applications both from the basic and applied research have emerged, turning the early ideas into a powerful paradigm for cell biology, neuroscience and medical research. This review aims at highlighting the basic concepts that are essential for a comprehensive understanding of optogenetics and some important biological/biomedical applications. Further, emphasis is placed on advancement in optogenetics-associated light-based methods for controlling gene expression, spatially-controlled optogenetic stimulation and detection of cellular activities.