Synthesis of unsaturated lactone moieties by asymmetric hetero Diels-Alder reactions with binaphthol-titanium complexes
Synthesis of unsaturated lactone moieties by asymmetric hetero Diels-Alder reactions with binaphthol-titanium complexes
复制标题
DOI：
10.1016/s0040-4039(00)02213-9
复制
发表时间：
2001-02-12
影响因子：
1.8
通讯作者：
Kalesse, M
中科院分区：
文献类型：
--
作者：
Quitschalle, M;Christmann, M;Kalesse, M
Natural products like ratjadone and callystatin A contain an alpha,beta -unsaturated lactone moiety which adds to the biological activity of these compounds. Here we report a rapid and practical access to lactone precursor 3 by an asymmetric hetero Diels-Alder reaction as the key step and its subsequent transformation into a suitable building block 4. (C) 2001 Elsevier Science Ltd. All rights reserved.
