A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization
A case of successful pregnancy after treatment of invasive cervical cancer with systemic chemotherapy and conization
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DOI：
10.1016/j.ygyno.2005.08.018
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发表时间：
2006-01-01
影响因子：
4.7
通讯作者：
Hasumi, K
中科院分区：
文献类型：
--
作者：
Kobayashi, Y;Akiyama, F;Hasumi, K
背景浸润性子宫颈癌的标准疗法会导致女性生育能力的丧失。我们报告一位希望保留生育能力的浸润性子宫颈癌患者成功怀孕，并接受全身化疗和锥切治疗。一名28岁的未经产妇女被诊断为一个大的30毫米直径的1B1期宫颈鳞状细胞癌。患者接受了连续4个疗程的低剂量BOMP（顺铂、博莱霉素、长春新碱和丝裂霉素C）全身化疗，通过检查锥切标本评估其产生了完全的病理学反应。两年后，患者怀孕，产下一名健康婴儿。该手术是一种保守治疗方法，以保留浸润性宫颈癌的生育能力。(c)2005年爱思唯尔公司All rights reserved.
Background. The standard therapy for invasive uterine cervical cancer Causes loss of the woman's fertility. We report a successful pregnancy in a patient who desired fertility-sparing management of invasive cervical cancer and was treated with systemic chemotherapy and conization.Case. A 28-year-old nulliparous woman was diagnosed with a large 30-mm-diameter stage 1B1 squamous cell carcinoma of the uterine cervix. The patient received 4 Courses of systemic chemotherapy with consecutive low-dose BOMP (cisplatin, bleomycin, vincristine and mitomycin C), which produced complete pathological response assessed by examination of specimens from conization. Two years later, the patient became pregnant, resulting in the birth of a healthy infant.Conclusion. This procedure is one method of conservative management to preserve fertility in invasive cervical cancer. (c) 2005 Elsevier Inc. All rights reserved.